A Randomized Placebo-Controlled Trial of Citalopram for Anxiety Disorders Following Traumatic Brain Injury
Annual rept. 1 Apr 2007-31 Mar 2008
HENRY M JACKSON FOUNDATION FOR THE ADVANCEMENT OF MILITARY MEDICINE ROCKVILLE MD
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The overarching goal of this project is to study the effects of a serotonin reuptake inhibitor SRI, citalopram, for the treatment of anxiety experienced by individuals after traumatic brain injury TBI. Specifically, this project seeks to treat individuals who meet criteria for DSM-IV diagnosis of Anxiety Disorder Due to a General Medical Condition, within 3 to 24 months of TBI. A randomized placebo controlled design with 1-year follow-up will be utilized to evaluate the effectiveness of citalopram in alleviating significant anxiety symptoms that cause significant distress and can lead to medical retirement of active duty soldiers.
- Anatomy and Physiology