Infrared Spectroscopic Imaging for Prostate Pathology Practice
Annual rept. 15 Feb 2008-14 Feb 2009
ILLINOIS UNIV CHAMPAIGN
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The report summarizes progress towards using Fourier transform infrared spectroscopic imaging for prostate pathology in year 2 of a 3 year award from the PCRP. The aim of the work is to enable histopathologic recognition without the use of human input or stains. The major accomplishments in the past year are 1 A genetic algorithm based method to distinguish benign from malignant epithelium using infrared spectroscopic imaging data was shown to be effective. Large scale validation is underway. 2 A combination of IR and conventional pathology imaging has been developed. This is a critical step to potential clinical translation, and 3 A combination of IR imaging and conventional pathology shows promising results that can be explained in the context of existing practice. Larger validation studies are needed.
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