Accession Number:

ADA503802

Title:

Evaluation of Barrier Skin Cream Effectiveness Against JP-8 Jet Fuel Absorption and Irritation

Descriptive Note:

Final rept. Nov 2003-Mar 2009

Corporate Author:

JACKSON (HENRY M) FOUNDATION FOR THE ADVANCEMENT OF MILITARY MEDICINE WRIGHT-PATTERSON AFB OH

Report Date:

2009-04-01

Pagination or Media Count:

47.0

Abstract:

The DoD and Air Force use large volumes of JP-8 annually. Due to the irritation produced by JP-8, the objective of this study was to obtain, formulate and experimentally select the most effective augmentation cream or lotion to inhibit skin exposure to liquid JP-8 during handling or after spills. Creams were tested first in vitro using cell diffusion chambers and then using the New Zealand White Rabbit model. Over-the-counter creams were first tested to evaluate the proof of concept of preventing dermal irritation with a barrier cream. Finally, formulated barrier creams were developed by two different companies and tested in-house. An effective barrier cream was not found using the rabbit model. The most effective protection against JP-8 remains personal protective equipment including gloves, and etc.

Subject Categories:

  • Anatomy and Physiology
  • Toxicology
  • Fuels
  • Protective Equipment

Distribution Statement:

APPROVED FOR PUBLIC RELEASE