Accession Number:

ADA503782

Title:

Process Research and Development of Antibodies as Countermeasures for C. botulinum

Descriptive Note:

Final rept. 1 Mar 2002-28 Jan 2009

Corporate Author:

NEBRASKA UNIV LINCOLN

Personal Author(s):

Report Date:

2009-02-01

Pagination or Media Count:

41.0

Abstract:

This final report describes the design and construction of a CGMP facility for yeast and bacteria on the first floor and basement of Othmer Hall, the home for the University of Nebraska-Lincoln Biological Process Development Facility. Total cost for construction was 11,165,740, with the University of Nebraska-Lincoln providing 5,179,226 46 of the funding, USAMRMC providing 4,958,049 45, and JVAP providing 1,028,465 9 . This final report also describes the expression, purification and media optimization of a monoclonal antibody against serotype A botulinum neurotoxin.

Subject Categories:

  • Biochemistry
  • Anatomy and Physiology
  • Medicine and Medical Research

Distribution Statement:

APPROVED FOR PUBLIC RELEASE