Accession Number:

ADA503749

Title:

Comparison of Clinical Presentation of Acute Myocarditis Following Smallpox Vaccination to Acute Coronary Syndromes in Patients <40 Years of Age

Descriptive Note:

Journal article

Corporate Author:

BRIGHAM AND WOMEN'S HOSPITAL BOSTON MA

Report Date:

2005-05-15

Pagination or Media Count:

5.0

Abstract:

Smallpox vaccine-associated myopericarditis may have a similar presentation to acute coronary syndrome ACS. The clinical records of 78 young patients 40 years of age presenting with ACS n16 or myocarditis after smallpox vaccination n62 were reviewed. Comparisons were made among clinical presentation, cardiac enzymes, echocardiographic findings, and electrocardiographic changes. The presence of cardiac risk factors or focal wall motion abnormalities on echocardiography were associated with a diagnosis of ACS. There was a trend toward earlier elevation of troponin-I and creatine kinase in patients with myocarditis compared with ACS.

Subject Categories:

  • Biochemistry
  • Anatomy and Physiology
  • Medicine and Medical Research
  • Military Forces and Organizations

Distribution Statement:

APPROVED FOR PUBLIC RELEASE