Accession Number:

ADA503213

Title:

An Efficient Synthesis of Dicycloalkylacetylenes: 1,2-Dicyclopropylethyne and (cyclopropylethynyl)cyclobutane (Preprint)

Descriptive Note:

Journal article

Corporate Author:

AIR FORCE RESEARCH LAB EDWARDS AFB CA SPACE AND MISSILE PROPULSION DIV

Report Date:

2008-11-05

Pagination or Media Count:

15.0

Abstract:

Lithium acetylides, generated from terminal acetylenes with n-BuLi in THF at -70 degrees C, react chemoselectively with omega-haloalkyl tosylate in the presence of 10 mole of Bu4I at 70 degrees C to furnish omega-haloalkyl acetylenes in very good yields. The omega-haloalkyl acetylenes were subject to intra-molecular alkylation with LDA to provide dicycloalkylethyne.

Subject Categories:

  • Organic Chemistry
  • Physical Chemistry

Distribution Statement:

APPROVED FOR PUBLIC RELEASE