Accession Number:

ADA495322

Title:

Accurate 3D Modeling of Breast Deformation for Temporal Mammogram Registration

Descriptive Note:

Annual rept. 1 Sep 2007-31 Aug 2008

Corporate Author:

UNIVERSITY OF SOUTH FLORIDA TAMPA

Personal Author(s):

• Goldgof, Dmitry

Report Date:

2008-09-01

Pagination or Media Count:

51.0

Abstract:

In this research project, we have developed mathematical model of breast deformation to simulate breast compression during mammographic imaging. We have developed two types of mammogram registration methods magnetic resonance imaging MRI guided registration and generic registration. Datasets have been constructed to validate the developed registrations methods. Mammogram registrations have been performed on concurrent mammograms using MRI guided and generic registration method, respectively. Also both registration methods have been applied onto temporal mammograms. Promising evaluation results demonstrate feasibility of the developed mammogram registration methods. The results also demonstrate that the developed registration methods would be very helpful in mammogram interpretation for improving accuracy of detection and diagnosis of breast cancer.

Descriptors:

• *MAMMOGRAPHY
• *BREAST CANCER
• DEFORMATION
• MAMMARY GLANDS
• MAGNETIC RESONANCE IMAGING
• DETECTION
• MATHEMATICAL MODELS
• DIAGNOSIS(GENERAL)

Subject Categories:

• Anatomy and Physiology
• Medicine and Medical Research

Distribution Statement:

APPROVED FOR PUBLIC RELEASE