Accession Number:

ADA494754

Title:

Prostate Dose Escalation by a Innovative Inverse Planning-Driven IMRT

Descriptive Note:

Final rept. 1 Nov 2004-31 Oct 2008

Corporate Author:

STANFORD UNIV CA

Personal Author(s):

• Xing, Lei

Report Date:

2008-11-01

Pagination or Media Count:

155.0

Abstract:

The goal of this project is to develop innovative inverse planning techniques for prostate radiation therapy. In the last funding period significant progress has been made toward the goal of the project. In the past funding year, the PI group has continued to advance prostate radiation therapy techniques. A few important milestones have been achieved toward the goal of the project. These include i Proposed a novel total-variation regularization based inverse planning technique for prostate IMRT ii Applied compressed sensing concept to IMRT and IMAT inverse planning and established a multi-objective optimization framework iii Developed a voxel-specific penalty scheme for TRV-based inverse planning iv Established a cine-EPID image retrospective dose reconstruction in IMRT dose delivery for adaptive planning and IMRT dose verification. These works are both timely and important and should lead to widespread impact on prostate cancer management.

Descriptors:

• *RADIOTHERAPY
• *PROSTATE CANCER
• VERIFICATION
• DETECTION
• DOSAGE

Subject Categories:

• Medicine and Medical Research
• Radiobiology

Distribution Statement:

APPROVED FOR PUBLIC RELEASE