Time-Resolved and Spectroscopic Three-Dimensional Optical Breast Tomography
Annual rept. 1 Apr 2007-31 Mar 2008
CITY COLL NEW YORK
Pagination or Media Count:
The research carried out during the current reporting period included a application and further refinement of optical tomographic imaging using independent component analysis OPTICA developed during the earlier reporting periods for locating and cross-section imaging of a tumor in a model cancerous breast assembled using ex vivo breast tissue specimens and b development of a new approach for detection of a target in a highly scattering turbid medium using near-infrared center of intensity time gated imaging. The OPTICA approach was able to detect, provide the location with an accuracy of 1 mm and cross section of the tumor in the model cancerous breast. It also identified two streaks of fibro-glandular tissues in the breast. The near-infrared center of intensity time gated imaging approach provided two-dimensional image of a piece of porcine liver within a slab of porcine tissue, and shows promise to evolve as a simple optical biomedical imaging approach.
- Medicine and Medical Research