Accession Number:

ADA492472

Title:

Time-Resolved and Spectroscopic Three-Dimensional Optical Breast Tomography

Descriptive Note:

Annual rept. 1 Apr 2007-31 Mar 2008

Corporate Author:

CITY COLL NEW YORK

Personal Author(s):

Report Date:

2008-04-01

Pagination or Media Count:

29.0

Abstract:

The research carried out during the current reporting period included a application and further refinement of optical tomographic imaging using independent component analysis OPTICA developed during the earlier reporting periods for locating and cross-section imaging of a tumor in a model cancerous breast assembled using ex vivo breast tissue specimens and b development of a new approach for detection of a target in a highly scattering turbid medium using near-infrared center of intensity time gated imaging. The OPTICA approach was able to detect, provide the location with an accuracy of 1 mm and cross section of the tumor in the model cancerous breast. It also identified two streaks of fibro-glandular tissues in the breast. The near-infrared center of intensity time gated imaging approach provided two-dimensional image of a piece of porcine liver within a slab of porcine tissue, and shows promise to evolve as a simple optical biomedical imaging approach.

Subject Categories:

  • Medicine and Medical Research

Distribution Statement:

APPROVED FOR PUBLIC RELEASE