Accession Number:

ADA482315

Title:

Continuous Performance in the Fur Seal: A Bridge to Extended Waking in Humans

Descriptive Note:

Final rept. 1 Sep 2002-31 Jul 2007

Corporate Author:

SEPULVEDA RESEARCH CORP NORTH HILLS CA

Personal Author(s):

Report Date:

2007-11-29

Pagination or Media Count:

10.0

Abstract:

We have discovered that dolphins and killer whales go without any extended periods of sleep and without any behavioral evidence for sleep for more than 1 month after birth. This indicates that any vital functions of sleep can be performed in the waking state, even early in the developmental period, a finding that has important implications for theories of sleep function and control. We have found a marked lateralization of acetylcholine release during unihemispheric sleep. We find that acetylcholine release is maximal in active waking, is significantly lower in quiet waking, does not differ from quiet waking level in REM sleep and is minimal in USWS and BSWS. In the first ever studies of cortical Hcrt release in any animal, we find evidence for lateralized release of Hcrt, maximal on the waking side of the cortex.

Subject Categories:

  • Anatomy and Physiology

Distribution Statement:

APPROVED FOR PUBLIC RELEASE