Accession Number:

ADA473056

Title:

Biocompatible and Biomimetic Self-Assembly of Functional

Descriptive Note:

Final rept. 6 Feb 2004-31 Dec 2006

Corporate Author:

NEW MEXICO UNIV ALBUQUERQUE DEPT OF CHEMICAL AND NUCLEAR ENGINEERING

Personal Author(s):

Report Date:

2007-10-03

Pagination or Media Count:

21.0

Abstract:

Understand cell-directed assembly and use it to direct the formation of new bionano interfaces and unique cellular behaviors -Investigated the inclusion of multiple amphipathic components to control and tailor interfacial structures and functions -Created new interfaces by incorporating non-native functional proteins to yield new functionalities Extend cell-directed assembly to immobilize various cell types -Encapsulated several new cell lines, including mammalian cells, in nano-structured hosts investigated the evolving nano-structure and bionano interface with grazing incidence small angle x-ray scattering along with epifluoresecence and confocal scanning laster -Used properties of nano-structure to incorporate nutrients and growth vital to different cell types in order to extend cell assembly

Subject Categories:

  • Test Facilities, Equipment and Methods
  • Mechanics
  • Biomedical Instrumentation and Bioengineering

Distribution Statement:

APPROVED FOR PUBLIC RELEASE