Accession Number:

ADA472397

Title:

Gene-Gene and Gene-Environment Interactions in the Etiology of Breast Cancer

Descriptive Note:

Final rept. 1 Jun 2002 31 May 2007

Corporate Author:

MEHARRY MEDICAL COLL NASHVILLE TN

Report Date:

2007-06-01

Pagination or Media Count:

65.0

Abstract:

The purpose of this proposal is to evaluate gene-gene and gene-environment interactions in the etiology of breast cancer in two ongoing case-control studies, the Shanghai Breast Cancer Study SBCS and the Nashville breast health Study NBHS and in a proposed case-control study, the Breast Cancer in West Africa Study BCAWS. An allelic variant of UGT1A1 allele28 was identified as a risk factor for postmenopausal breast cancer in Chinese women. A proposal was submitted and funded for the BCAWS study through U54-CA9140801 Adunyah PI. Samples and surveys acquired from the BCAWS study are currently being analyzed.

Subject Categories:

  • Genetic Engineering and Molecular Biology
  • Medicine and Medical Research

Distribution Statement:

APPROVED FOR PUBLIC RELEASE