Accession Number:

ADA470792

Title:

Enzymatic Decontamination of Environmental Organophosphorus Compounds

Descriptive Note:

Final rept. 5 Jun 2003-4 Dec 2006

Corporate Author:

MIAMI UNIV CORAL GABLES FL

Personal Author(s):

Report Date:

2006-12-04

Pagination or Media Count:

13.0

Abstract:

This final report describes the research performed during the award period June 5, 2003 to December 4, 2006. The main thrust of the research project was to investigate the surface chemistry of and molecular interactions between OP compounds and enzymes. The objective were i to characterize the Langmuir films of organophosphorus acid hydrolase OPH and organophosphorus acid anhydrase OPAA by studying their interfacial and spectroscopic properties at airwater interface ii to investigate the molecular interactions between OPH and OPAA and the OP compounds using Polarization Modulation FTIR spectroscopy iii to characterize the topography of OPH and OPAA by scanning probe and environmental scanning electron microscopies iv to characterize the basic features of AChE biosensor based on LB film technology. v to simulate the active site of acetylcholinesterase AChE

Subject Categories:

  • Biochemistry

Distribution Statement:

APPROVED FOR PUBLIC RELEASE