Optimization of Tomosynthesis Imaging for Improved Mass and Microcalcification Detection in the Breast
Annual summary rept. 15 Mar 2006-14 Mar 2007
CHICAGO UNIV IL
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Although considerable progress has been made for the breast tomosynthesis, there are still some issues should be addressed before it becomes suitable for routine clinical use 1 development of accurate and efficient algorithms for reconstructing 3D breast images from tomosynthesis data, 2 the effect of various physical factors on image quality. During the first year of this research, we have implemented and investigated the TV-based algorithm for image reconstruction in breast tomosynthesis, and investigated the convergence property of the TV-based algorithm under different data conditions and different constraint parameters. We have also conducted numerical studies to investigate the image reconstruction by use of the TV-based algorithm and the existing EM and ART algorithms for different imaging configurations in breast tomosynthesis. Furthermore, we have investigated some physical factors such as cone-beam data noise and non-isotropic spatial resolution on tomosynthesis images.
- Medicine and Medical Research