Accession Number:

ADA470040

Title:

Accumulation of Large Amounts of Hyperpolarized Xe-129 & Applications to Xe-129 Spectroscopy

Descriptive Note:

Final rept. 10 Jun 2002-09 Jun 2006

Corporate Author:

PRINCETON UNIV NJ DEPT OF PHYSICS

Personal Author(s):

Report Date:

2007-01-15

Pagination or Media Count:

11.0

Abstract:

We have studied the physics underlying the production, accumulation, and cryogenic separation of hyperpolarized xenon-129. This research has led to a dramatically improved understanding of the physics behind nuclear relaxation in solid xenon and resolved long-standing discrepancies between theoretical predictions and experimental observation. The information gained from these experiments allowed us to produce greater quantities of hyperpolarized 129Xe with higher nuclear polarization. This in turn permitted us to begin cutting-edge studies applying hyperpolarized 129Xe nuclear magnetic resonance NMR spectroscopy to samples of biological interest. Specifically, we performed preliminary experiments which demonstrated that hyperpolarized 129Xe spectroscopy may be useful in the diagnosis of atherosclerosis.

Subject Categories:

  • Medical Facilities, Equipment and Supplies
  • Atomic and Molecular Physics and Spectroscopy
  • Medicine and Medical Research

Distribution Statement:

APPROVED FOR PUBLIC RELEASE