Exploring Early Detection Methods: Using the Intraductal Approach to Predict Breast Cancer
Annual summary rept. 15 Jun-14 Nov 2006
CALIFORNIA UNIV SAN FRANCISCO
Pagination or Media Count:
Nipple aspiration ductal lavage and ductography are methods of obtaining breast fluids from women who are neither pregnant or lactating. Breast cells in these fluids can be classified as either normal or as showing various abnormalities including hyperplasia atypical hyperplasia and cancer. In previous follow-up studies of women who participated in breast fluid and tissue studies it was shown that women with proliferative cytology hyperplasia or atypical hyperplasia were significantly more likely to develop breast cancer than women with normal cytologic findings in breast fluids or than women from whom fluid could not be obtained. Fabian et al. 2000 Wrensch et al. 2001 This study followed an additional cohort of women from Santa Barbara CA that had fluids drawn between 1970-1990. Statistical methods of association were used to determine if women with abnormal ctyologic findings developed breast cancer at a higher rate than women with normal cytologic findings or women from whom fluid could not be obtained. Overall 10 93 of the 946 women developed breast cancer during the follow-up period.
- Anatomy and Physiology
- Medicine and Medical Research