Design and Development of Nanoscale Biomotor Power Units
Final rept. 2 Aug 2003-1 Nov 2006
UTAH STATE UNIV LOGAN DEPT OF CHEMISTRY AND BIOCHEMISTRY
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1. We have continued to refine our theoretical model for the design of a bacterial cell powered motor. 2. We have determined what types of surfaces bind motile bacterial cells. 3. We have monitored surface adhered bacterial cell motility using fluorescent dyes and found that cells remain alive and motile for more than 4 hours. 4. We have discovered that E. coli bacterial cells will not bind to surface dot features with a diameter of 1.2 micrometers or smaller. 5. We have designed and fabricated holed surfaces that bind motile bacterial cells in a nose-on fashion. 6. We have used DPN to attach bacterial cells to surfaces. 7. We have obtained and attached CheY deficient Pseudomonas aeruginosa smooth swimming bacterial cells to prefabricated micro-array surfaces. 8. We have generated an initial design and fabricated a prototype micro-scale biomotor. 9. We have proof-of-concept that motile bacterial cells can spin a device. Progress in the last four years has been excellent, and included the publication of three manuscripts Small, Talanta and, Langmuir. We currently have at least two additional manuscripts in preparation.
- Physical Chemistry
- Electrical and Electronic Equipment