Accession Number:

ADA463484

Title:

Development of the Meharry Medical College Prostate Cancer Research Program

Descriptive Note:

Annual rept. 1 Mar 2005-28 Feb 2006

Corporate Author:

MEHARRY MEDICAL COLL NASHVILLE TN

Personal Author(s):

Report Date:

2006-03-01

Pagination or Media Count:

31.0

Abstract:

African Americans AA are disproportionately affected by prostate cancer PCa for reasons including, biologic tumor differences, genetic predisposition, differential exposures, lack of access to prostate specific antigen PSA testing, inadequate access to health care, paucity of minority PCa investigators, and low accrual of AAs in clinical trials. We propose a research team at an HBCU to study the molecular, genetic, dietary, and body fat patterns in the pathogenesis of PCa disparity among AA and African men. There is substantial urology, oncology, epidemiology, nutrition and other expertise in both institutions, now developing this program at MMC, by training new and junior minority investigators, maintaining lasting partnership with mentors, and establish viable community network ties. One project will investigate health care seeking behavior of AA, another will investigate the role of lycopene in PCa risk, a third will look at genetic risk factors, and two studies will study the growth inhibitory effect of Thalidomide and other agents on PCa cell lines. The program has attracted graduate students, has identified, and is currently in the process of hiring a second post-doctoral fellow.

Subject Categories:

  • Medicine and Medical Research

Distribution Statement:

APPROVED FOR PUBLIC RELEASE