Accession Number:

ADA463237

Title:

Bone Growth, Mechanical Stimulus and IGF-1

Descriptive Note:

Final rept. 10 Seo 2001-10 Sep 2006

Corporate Author:

CHILDREN'S HOSPITAL LOS ANGELES CA

Personal Author(s):

Report Date:

2006-10-01

Pagination or Media Count:

51.0

Abstract:

The purpose of this study was to assess the potential for brief periods of low magnitude high frequency mechanical stimulation signals in the musculoskeletal system. The major findings were that short bouts of extremely low-level mechanical signals, several orders of magnitude below that associated with vigorous exercise, increased bone and muscle mass in the weight bearing skeleton of young adult females with low bone density. Ultimately, this information could be of great benefit to enhance musculoskeletal development and decrease the risk for stress fractures in military recruits. Moreover, should these musculoskeletal persist through adulthood, this intervention may prove a deterrent to osteoporosis in the elderly.

Subject Categories:

  • Anatomy and Physiology

Distribution Statement:

APPROVED FOR PUBLIC RELEASE