Accession Number:

ADA462198

Title:

Caffeine, Adenosine Receptors and Estrogen in Toxin Models of Parkinson's Disease

Descriptive Note:

Annual rept.

Corporate Author:

MASSACHUSETTS GENERAL HOSPITAL BOSTON

Personal Author(s):

• Schwarzshild, Michael A.

Report Date:

2006-10-01

Pagination or Media Count:

36.0

Abstract:

Identifying the mechanisnms by which caffeine and more specific A2A antagonists protect dopaminergic neurons in muttiple toxin models of Parkinsons disease PD will advance our knowledge of the pathophysiology epidemiology and therapeutics of PD.

Descriptors:

• *CAFFEINE
• *PARKINSONS DISEASE
• THERAPY
• PATHOPHYSIOLOGY
• DOPAMINE
• MOTOR NEURONS
• ESTROGENS
• ADENOSINE
• EPIDEMIOLOGY
• TOXINS AND ANTITOXINS
• RECEPTOR SITES(PHYSIOLOGY)

Subject Categories:

• Biochemistry
• Anatomy and Physiology
• Medicine and Medical Research

Distribution Statement:

APPROVED FOR PUBLIC RELEASE