Evaluation of Novel Hemostatic Agents in a Swine Model of Non-Compressible Hemorrhage
Final rept. 3 Jul 2003-2 Jul 2005
HAEMATOLOGIC TECHNOLOGIES INC ESSEX JUNCTION VT
Pagination or Media Count:
Uncontrolled hemorrhage is the leading cause of death from wounds on the battlefield, accounting for over 50 of mortality. Hemorrhage is also the second leading cause of death in civilian trauma. There is a significant correlation between increased evacuation time and deaths due to combat injuries which increases proportionally with increasing evacuation time. Of the increased death due to delayed evacuation, 62 are the result of hemorrhage. This represents a group of casualties who bleed from wounds that are not immediately fatal. Approximately 80 of the hemorrhagic combat deaths are from wounds that are not compressible accessible for manual pressure. Currently, there is no method available forward of the operating table that can provide hemorrhage control for non-compressible hemorrhage. In spite of the common use of pharmacologic methods for decreasing blood loss in elective surgeries and specific coagulopathies in which large blood losses are expected, the potential for use to aid homeostasis during traumatic hemorrhage has not been adequately studied.
- Anatomy and Physiology
- Medicine and Medical Research