Accession Number:

ADA459727

Title:

A Training Program in Breast Cancer Research Using NMR Techniques

Descriptive Note:

Final rept. 1 Jul 2000-30 Jun 2006

Corporate Author:

HOWARD UNIV WASHINGTON DC

Personal Author(s):

Report Date:

2006-07-01

Pagination or Media Count:

86.0

Abstract:

This is a six year training program in breast cancer research using NMR techniques. This program has supported seven predoctoral students and five postdoctoral students. All the trainees have learned the theory and instrumentation of MRI. They have been actively involved in one of the seven research projects 1 NMR studies of phosphorus metabolites of breast cancer cells using an improved cell perfusion system 2 Segmentation of mammographic masses 3 Establishment of an image database for computer-aided-diagnosis CAD research development 4 F19 NMR detection of trifluoperazine crossing Blood-Brain-Barrier through Pgp modulation 5 Tumor-targeted MR Contrast Enhancement by Anti-transferrin Receptor scFv-Immunoliposome Nanoparticles 6 MRI and histological correlations of cortical brain volumes in APPPS1 mice 7 Enhanced molecular imaging with fused optical and MRI images. The trainees have attended the weekly seminars in the Cancer Center and also attended a special NMR seminar series in the Department of Radiology. Eight papers have been published and 16 abstracts have been presented in the national and international meetings. Five grants including a USAMRMC postdoctoral award have received.

Subject Categories:

  • Medicine and Medical Research
  • Atomic and Molecular Physics and Spectroscopy

Distribution Statement:

APPROVED FOR PUBLIC RELEASE