Temporal and Spatial Dynamics of DNA Topoisomerase 1 in Prostate Cancer
Final rept. 15 Dec 2001-14 Jan 2006
MISSISSIPPI UNIV UNIVERSITY
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The purpose of this proposal was to investigate the response of prostate cancer to a series of camptothecin analogs, which are drugs that target DNA topoisomerase I. This final report summarizes the accomplishments toward the original goals of the project. We note that while some experimental problems were encountered that limited the completion of all tasks, good progress was made overall on the proposed research.
- Anatomy and Physiology
- Medicine and Medical Research