Accession Number:

ADA459174

Title:

Temporal and Spatial Dynamics of DNA Topoisomerase 1 in Prostate Cancer

Descriptive Note:

Final rept. 15 Dec 2001-14 Jan 2006

Corporate Author:

MISSISSIPPI UNIV UNIVERSITY

Personal Author(s):

Report Date:

2006-07-01

Pagination or Media Count:

12.0

Abstract:

The purpose of this proposal was to investigate the response of prostate cancer to a series of camptothecin analogs, which are drugs that target DNA topoisomerase I. This final report summarizes the accomplishments toward the original goals of the project. We note that while some experimental problems were encountered that limited the completion of all tasks, good progress was made overall on the proposed research.

Subject Categories:

  • Anatomy and Physiology
  • Medicine and Medical Research

Distribution Statement:

APPROVED FOR PUBLIC RELEASE