Accession Number:

ADA458977

Title:

Behavioral and Biological Effects of Housing Conditions and Stress in Male Rats - Relevance to Heart Disease

Descriptive Note:

Corporate Author:

UNIFORMED SERVICES UNIV OF THE HEALTH SCIENCES BETHESDA MD

Personal Author(s):

Report Date:

2006-08-01

Pagination or Media Count:

104.0

Abstract:

The present experiment examined the effects of environmental enrichment and stress on behavioral and biological measures relevant to cardiovascular disease risk i.e. plasma corticosterone levels elevated plus maze locomotor activity in an open field chamber body weight and food consumption and heart morphology. Seventy-two Sprague-Dawley rats were raised in enriched environments social or social and physical enrichment or non-enriched environments for a total of 48 days. Half of the animals were placed in stress conditions in which they received 14 days 20 minuteslday of restraint stress and the other half of the animals were placed in a no-stress condition.

Subject Categories:

  • Medicine and Medical Research
  • Stress Physiology

Distribution Statement:

APPROVED FOR PUBLIC RELEASE