Vascular Materials for Human Heat Management and Wound Healing
Final technical rept., 30 Jun 2004-31 Dec 2005
CORNELL UNIV ITHACA NY
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The key to our experimental approach to the creation of Vascular Materials is the development of material syntheses and methods of micro-fabrication that allow us to embed micro-fluidic structure directly within hydrogels. For the operation and characterization of systems Artificial Leaves, Wound Dressings, and Tissue Scaffolds based on Vascular Materials, we have developed experiments to control and monitor fluxes of heat and mass in an automated fashion. In parallel, we have developed a theoretical basis for the design and operation of this new class of active materials. Highlights 1 Development of techniques to embed functional micro-fluidic structure within organic hydrogels. 2 Development of a complete theory and experimental characterization of heat and mass transfer in transpiration from hydrated materials. This work is the foundation of our development of a flexible heat pipe. 3 Development of an Active Wound Dressing that allows for external management of the mass exchange and mechanical stimulation of the wound bed. 4 Development of the first micro-fluidic scaffold for three-dimensional cell culture and tissue engineering.
- Medicine and Medical Research