Accession Number:

ADA456012

Title:

Targeting MRS-Defined Dominant Intraprostatic Lesions with Inverse-Planned High Dose Rate Brachytherapy

Descriptive Note:

Annual rept. 26 Jan 2005-25 Jan 2006

Corporate Author:

SAN FRANCISCO UNIV CA

Personal Author(s):

Report Date:

2006-02-01

Pagination or Media Count:

26.0

Abstract:

During this second year, we have obtained CHR approval December 2004 from the three step process G.U., P.R.C. and C.H.R. committees at UCSF. Patient enrollment will begin immediately after receiving CHR approval from D.O.D. We have developed a deformable image registration method to improve the quality of registration of probe-in MRS data for probe-out radiation treatment planning. A similarity index SI of 98.1 was obtained for rigid probe patient data. We have also obtained a class solution for the boost of DIL defined by MRI MRSI, as well as for the sparing of organs at risk including bladder, rectum, urethra and penile bulb.

Subject Categories:

  • Anatomy and Physiology
  • Medicine and Medical Research

Distribution Statement:

APPROVED FOR PUBLIC RELEASE