Accession Number:

ADA455912

Title:

Effectiveness of the 2003/2004 Influenza Vaccine Among U.S. Military Basic Trainees: A Year of Suboptimal Match Between Vaccine and Circulating Strain

Descriptive Note:

Rept. for 2003-2004

Corporate Author:

NAVAL HEALTH RESEARCH CENTER SAN DIEGO CA

Personal Author(s):

• Russell, Kevin L.
• Ryan, Margaret A.
• Hawksworth, Anthony
• Freed, Nikki E.
• Irvine, Marina
• Daum, Luke T.

Report Date:

2004-06-03

Pagination or Media Count:

20.0

Abstract:

Effectiveness of the 2003-04 influenza vaccine was evaluated at 5 military basic training centers throughout the United States. Data from surveillance conducted in December and January 20032004 in this highly vaccinated population were evaluated. During this period 10.6 37350 of specimens were positive for influenza A. A 14-day period after vaccination was considered the period prior to immune protection vaccine effectiveness VE was calculated based on febrile respiratory illness presentation and laboratory confirmation of influenza before or after this 14-day period. Thirty-two cases presented within 14 days of vaccination and 5 cases presented beyond 14 days from vaccination. VE in this population was estimated to be 94.4 for laboratory-confirmed influenza. In contrast VE was only 13.9 for influenza-like illness without a laboratory confirmation.

Descriptors:

• *INFLUENZA
• *VACCINES
• MILITARY PERSONNEL
• SIGNS AND SYMPTOMS
• ILLNESS
• RESPIRATORY DISEASES
• TRAINEES
• IMMUNIZATION
• FEVERS

Subject Categories:

• Pharmacology

Distribution Statement:

APPROVED FOR PUBLIC RELEASE