Assessment of Antibiotic Resistant Commensal Bacteria in Food
OHIO STATE UNIV COLUMBUS
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The rapid emergence of antibiotic resistant ART pathogens is a major public health concern. Although antibiotic resistance AR in foodborne pathogens has been studied extensively, the contribution of foodborne commensals in disseminating the resistance genes has been neglected in the past. Foodborne pathogens only account for a very small portion of microbes associated with food meanwhile, AR encoding genes can be transferred readily from commensals to pathogens by natural gene transfer mechanisms. Horizontal transmission of genetic material from one organism to another has been established as a major mechanism for the expedited development of resistance. The impacts of antibiotic applications in clinical treatments, veterinary medicine, animal husbandry practices and animal feed on the emergence of antibiotic resistance AR have been well-documented. However, knowledge on other major routes in the dissemination of AR is limited. This information is essential to properly evaluate the contribution of food chain in the evolvement of AR pathogen, particularly in susceptible host populations.
- Medicine and Medical Research