BRCA1 Protein Complexes: Dynamic Changes and Functions Important in Breast Cancer
Annual summary rept. 15 Mar 2005-14 Mar 2006
HARVARD MEDICAL SCHOOL BOSTON MA
Pagination or Media Count:
In the past year, I have made substantial progress towards completion of the tasks outlined in my Statement of Work. I have continued to study the intrinsic transcriptional activity of BRCA1 in the fully purified system, and I have described distinct mechanisms for transcriptional stimulation and repression. These activities recapitulate the in vivo transcriptional functions of BRCA1.
- Genetic Engineering and Molecular Biology
- Anatomy and Physiology