Accession Number:

ADA455716

Title:

A Controlled Laboratory Experiment to Compare Lesions Resulting from Application of Mustard, Lewisite, and Nitrogen Mustards to the Skin of the Forearms of Humans

Descriptive Note:

Corporate Author:

NAVAL RESEARCH LAB WASHINGTON DC

Personal Author(s):

• Daily, L. E.
• Clark, J. W.
• Stolp, B. N.
• Conner, J. C.

Report Date:

1944-09-01

Pagination or Media Count:

34.0

Abstract:

Vapor cups containing mustard, Lewisite, and nitrogen mustard, HN3, were employed to produce lesions of comparable size and severity on the forearms of humans. In two 2 other series of tests, drops of equal weight and drops of equal volume of each of the above vesicants were applied to the forearms of men to compare the vesicant powers of the agents and to study the type of lesion produced in each case. Color photographs, both still and motion picture, were taken throughout the experiment to snow each lesion developing, reaching a weak and subsiding. To the best of our knowledge, no previous experiments have been performed by placing the three 3 basic types of Eases mustard, arsenicals, and nitrogen mustards on the same individual, with systematic observation, including pictures, from the time of application of the pas through the development and healing of the lesion. It is felt that these observations will be an aid to other investigators who are either new in this field, or do not have the facilities for running this type of experiment.

Descriptors:

• *LABORATORY TESTS
• *MUSTARD AGENTS
• *LESIONS
• *NITROGEN MUSTARDS
• *LEWISITE
• TEST AND EVALUATION
• HUMANS
• ARSENIC COMPOUNDS
• ARMS(ANATOMY)
• HEALING
• OBSERVATION
• NITROGEN
• VAPORS
• VOLUME

Subject Categories:

• Anatomy and Physiology
• Test Facilities, Equipment and Methods
• Chemical, Biological and Radiological Warfare

Distribution Statement:

APPROVED FOR PUBLIC RELEASE