Inverse Problems and Model Validation: An Example from Latent Virus Reactivation
NORTH CAROLINA STATE UNIV AT RALEIGH CENTER FOR RESEARCH IN SCIENTIFIC COMPUTATION
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We consider a least squares inverse problem with a model for inducer-mediated reactivation of latent viruses. We illustrate the difficulties associated with the lack of sufficient data quantity as well as form in such problems. The modeling and estimation efforts described suggest new experiments as well as needed model extensions.
- Statistics and Probability