Quantitative Studies of Sublingual PCO2 as a Resuscitation End-Point in the Diagnosis and Treatment of Hemorrhagic Shock
Final rept. for 11 Dec 2002-30 Sep 2005
VIRGINIA COMMONWEALTH UNIV RICHMOND
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This clinical study is examining the relationship between sublingual PCO2 PslCO2 to real-time changes in microcirculatory blood flow of the sublingual mucosa in victims of traumatic and hemorrhagic shock. This relationship will assist in understanding the direct effects of blood loss on sublingual perfusion and thus PslCO2 as a reflection of this. The study is also comparing the sensitivity and specificity of PslCO2 to detect compensated shock states and the severity of uncompensated shock to other commonly utilized methods such as global oxygen delivery and consumption, systemic lactate and base, and other regional measures of perfusion.
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