Rapid Molecular Fingerprinting of Pathogens
Final rept. 1 Mar 2005-31 May 2006
CALIFORNIA UNIV SANTA BARBARA
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The first aim of this project was to identify a set of ligands that bind specifically to each member of a panel of related alpha viruses, namely, equine encephalitis viruses EEV. The second aim was to develop a bacterial cell-based array platform that can be used to detect viruses present in serum or other complex mixtures. During the course of this project we generated a set of peptides that bind to Venezuelan or Western EEV VEEV, WEEV, and investigated a microfluidic array method to pattern these affinity reagent displaying cells into arrays, allowing their potential application for detection assays.
- Organic Chemistry