Accession Number:

ADA454900

Title:

Unique Approaches to Androgen Effects on Prostate Cancer

Descriptive Note:

Annual rept. 19 Jan 2005-18 Jan 2006

Corporate Author:

SAINT LUKE'S HOSPITAL CENTER NEW YORK

Personal Author(s):

Report Date:

2006-02-01

Pagination or Media Count:

21.0

Abstract:

Sex hormone-binding globulin SHBG is a plasma protein that binds androgens. It also is a transducer of androgen signaling at the plasma membrane of prostate cancer cells. We have found that the human prostate cancer cell line, LNCaP, in addition to having a receptor for SHBG RSHBG, produces its own SHBG. We hypothesize that local regulation

Subject Categories:

  • Biochemistry
  • Medicine and Medical Research
  • Stress Physiology

Distribution Statement:

APPROVED FOR PUBLIC RELEASE