Multifunctional Magnetic Nanowires for Biomagnetic Interfacing Concepts
Final rept. 15 Jun 2002-15 Dec 2005
JOHNS HOPKINS UNIV BALTIMORE MD
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A technique of increasing importance in biotechnology is the manipulation of cells and biomolecules with small magnetic particles. In this research program, we developed a new type of carrier particle, multifunctional magnetic nanowires, which possess tunable magnetic and chemical properties. These nanowires can carry out multiple tasks e.g. binding multiple types of molecules, probing chemical activity in specific regions of a cell, and responding to light as well as to magnetic fields. Among the DoD relevant applications envisioned for the nanowires are new techniques for biosensing, novel approaches to tissue engineering, and a variety of diagnostic and therapeutic approaches including rapid drug delivery, gene therapy and high-efficiency cell sorting. This program carried out the development steps necessary to demonstrate the feasibility of these applications.
- Biomedical Instrumentation and Bioengineering