Accession Number:

ADA453068

Title:

Artificial Nucleases as Antiviral, Antibacterial Agents

Descriptive Note:

Briefing charts

Corporate Author:

LOYOLA UNIV NEW ORLEANS LA

Report Date:

2003-11-19

Pagination or Media Count:

20.0

Abstract:

Objective Develop strongly binding artificial nucleases, with enhanced sequence-recognition and stability for anti-bacterial and anti-viral applications. Approach Synthesize small metal-chelator complexes suitably modified for coupling to oligonucleotides ODN as nuclease-like probes for binding to target viral RNA sequences.

Subject Categories:

  • Biochemistry
  • Pharmacology

Distribution Statement:

APPROVED FOR PUBLIC RELEASE