Metallic Nanoprobes for Enhanced Raman and Fluorescence Spectroscopy
PHYSICAL SCIENCES INC ANDOVER MA
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Metallic Nanoprobe Fabrication Current approaches include deposition of metal island films on substrates and salt-induced aggregation of metallic colloids good enhancement is observed but reproducibility is a serious issue variability in nanoprobe fabrication is responsible for assay variability. Our approach is to synthesize metallic nanosphere structures with controlled interparticle spacing to exploit significant field enhancement between particles start with simplest structure nanosphere dimer dimers permit fully solution-based assay.
- Atomic and Molecular Physics and Spectroscopy
- Polymer Chemistry
- Metallurgy and Metallography