Accession Number:

ADA453066

Title:

Metallic Nanoprobes for Enhanced Raman and Fluorescence Spectroscopy

Descriptive Note:

Briefing charts

Corporate Author:

PHYSICAL SCIENCES INC ANDOVER MA

Personal Author(s):

Report Date:

2003-11-18

Pagination or Media Count:

24.0

Abstract:

Metallic Nanoprobe Fabrication Current approaches include deposition of metal island films on substrates and salt-induced aggregation of metallic colloids good enhancement is observed but reproducibility is a serious issue variability in nanoprobe fabrication is responsible for assay variability. Our approach is to synthesize metallic nanosphere structures with controlled interparticle spacing to exploit significant field enhancement between particles start with simplest structure nanosphere dimer dimers permit fully solution-based assay.

Subject Categories:

  • Atomic and Molecular Physics and Spectroscopy
  • Biochemistry
  • Polymer Chemistry
  • Metallurgy and Metallography

Distribution Statement:

APPROVED FOR PUBLIC RELEASE