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A Multdisciplinary Evaluation of Traumatic Brain Injury: Early Predictors of Outcome

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Annual rept. 1 Apr 2004-31 Mar 2005

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The purpose of this study is to identify a cohort of patients with mild traumatic brain injury and follow them for one year post-injury to determine injury outcomes and identify factors that best predict long-term sequelae. The second year has been dedicated to continued subject recruitment and follow-up. Modifications were made to the study design to enhance recruitment. Human subjects approval was obtained from both the University and Army review hoards. Data entry and validation are ongoing, a process which also includes data back-up and migration. Laboratory protocols continue for the collection, storage, and processing of blood samples for the S-bob tests. We currently have preliminary data on 60 samples. The processes by which the Balance Master data are collected and stored have been finalized. It is anticipated that within the next year, we will be able to begin preliminary data analysis as we have now begun one-year follow-up on subjects. As of March 31, 2005, 78 subjects have been recruited. Based on a series of meetings with the Pl and the co- investigators, protocol modifications were made to enhance subject enrollment and it is already apparent that these modifications have been effective in increasing enrollment.

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  • Biology
  • Anatomy and Physiology

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