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Relationship Between Mammographic Density and IGF Levels Among Hispanic and Non-Hispanic White Women

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Annual summary rept. 15 Jul 2004-14 Jun 2005

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The purpose of this study is to use information collected from the parent study, the Womens Breast and Bone Density study WBBDto investigate the relationship between breast density and IGF levels in pre and postmenopausal Hispanic and non-Hispanic White women. The parent study was completed by the May 31, 2003. In all, recruitment was a lower than expected for the Hispanic women, but all recruitment goals were either met or exceed in the non-Hispanic White women. The total numbers are 60 premenopausal Hispanic women, 75 premenopausal non-Hispanic White women, 28 postmenopausal Hispanic women, and 78 poatmenopausal White women. The serum and plasma samples have been collected for the Insulin-like Growth Factor IGF and Insulin-like Growth Factor Binding Protein lGFBP assays used in this study including lGF-1, lGFBP-3, and Free lGF-1, however, the actual analysis will be completed in October 2003 - November 2003. The mammographic density measurements are currently being finalized and will be merged with the data collected from questionnaires, physical measurements, and the dual energy x-ray absorptiometry DXA scan. When the laboratory analyses are complete, the results of those tests will be merged with the clean WBBD data so that the analysis can be completed and manuscripts written.

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  • Anatomy and Physiology
  • Medical Facilities, Equipment and Supplies

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