Accession Number:

ADA439254

Title:

Magnetic Resonance Imaging of Polymeric Drug Delivery Systems in Breast Cancer Solid Tumors

Descriptive Note:

Annual summary rept. 1 Jul 2004-30 Jun 2005

Corporate Author:

MARYLAND UNIV BALTIMORE

Personal Author(s):

Report Date:

2005-07-01

Pagination or Media Count:

11.0

Abstract:

The overall purpose of this research is to develop a polymeric drug delivery system containing magnetic resonance contrast agents for the treatment of breast cancer. This drug-imaging agent delivery system will allow the follow up of the fate of the drug delivery system and its relation to reduced tumor mass, improved efficacy and reduced toxicity in individual patients. In year one progress was made in the following areas 1 Synthesis of polymer-linked contrast agent conjugates 2 Physicochemical characterization of polymer-linked contrast agent conjugates 3 Relaxivity and stability measurements of polymer-linked contrast agent conjugates. In addition I completed my coursework overall UPA3.6, presented the results in the 2005 Era of Hope Meeting, and participated in other scientific meetings related to my field.

Subject Categories:

  • Medicine and Medical Research

Distribution Statement:

APPROVED FOR PUBLIC RELEASE