Dietary Seaweed and Early Breast Cancer: A Randomized Trial
Annual rept. 1 May 2004-30 Apr 2005
SOUTH CAROLINA UNIV COLUMBIA
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The purpose of this research is to investigate whether eating brown seaweed Undaria pinnatifida can influence breast cancer risk. Brown seaweeds are popular in Japan, where the incidence of breast cancer is about 16 the rate of that reported for American women. In several animal studies of diet and cancer, adding seaweed to the normal diet resulted in longer healthy lives. In particular, we will examine cell surface binding characteristics and protein expression associated with the consumption of dietary seaweeds by women who have been treated for Stage 3 breast cancer. To date, progress has been limited by the lack of approval from HSRRB Proposal Log Number BC972552, HSRRB Log Number A-8050, with modifications. Modifications have been submitted in March, the Memorandum for Record has been filed, and we are completing the scientific review and modifications of the study. Final approval has not yet been granted. However, when this grant was first awarded in 1999 to the University of Massachusetts, we did a preliminary study to assess potential toxicity of dietary seaweed. The first paper on iodine content in commercially available seaweeds has been published, as has a review of the health effects and bioavailability of seaweed iodine in brown seaweeds.
- Medicine and Medical Research