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A Method for Simulating Mammograms

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Final addendum rept. 1 Aug 2003-31 Jul 2004

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This project is to facilitate research in digital mammography and related technologies, in particular computer-aided diagnosis CAD and image processing. A major limitation to the rapid development and subsequent clinical implementation of these technologies is the lack of a standardized set of mammorgrams with absolute truth e.g., exact location and extend of a cancer to be used in development and evaluation. We are developing a method to produce computer-simulated mammograms. The approach is to model the creation of the mammogram on the computer -- all steps from x rays exiting the breast to the image being displayed on a light box. The basic model, which we have developed previously, has been improved and is combined with accurate information of the appearance of normal breast anatomy and of benign and malignant breast lesions. These are obtained from high quality images of cadawer breasts and biopsy specimens. our approach is similar to that of Van Metter et al. who modeled chest radiographs Van Metter 1986. We believe that this technique can produce simulated mammograms that appear to be actual mammograms. This hypothesis is being tested by performing quantitative comparisons of simulated and real mammograms.

Subject Categories:

  • Medicine and Medical Research
  • Computer Programming and Software

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