Accession Number:

ADA434638

Title:

A Prospective Randomized Clinical Trial of Celecoxib for the Control of Symptomatic Plexiform Neurofibroma in Neurofibromatosis 1

Descriptive Note:

Final rept. 2 Jan 2004-1 Jan 2005

Corporate Author:

MASSACHUSETTS GENERAL HOSPITAL BOSTON WELLMAN LABS OF PHOTOMEDICINE

Personal Author(s):

Report Date:

2005-02-01

Pagination or Media Count:

6.0

Abstract:

The purpose of the project was to develop the infrastructure necessary to run a multi-center clinical trial of a novel medical therapy for patient with NF1. To this end, a consortium of seven institutions was developed, each with expertise in treating patients with NF1 or tumors of the nervous system. Important accomplishments include the establishment of a clinical protocol for running the trial naming a Steering Committee, Data and Safety Monitoring Board, and Medical Monitor and partnering with Pfizer, Inc, and PharmaContent, Inc. to run the trial. The protocol was submitted for approval at the Institutional Review Board at the sponsoring institution. This work culminated in the submission of a application for a Clinical Trial Award through the Department of Defense in June, 2005 month 6 of the grant period.

Subject Categories:

  • Anatomy and Physiology
  • Medicine and Medical Research

Distribution Statement:

APPROVED FOR PUBLIC RELEASE