Genetic Risk of Breast Cancer Distress and Immune Response
Annual summary rept. 5 Mar 2004-4 Mar 2005
ALABAMA UNIV IN BIRMINGHAM
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Based on Selyes framework of Physiological Response to Stress and Lazarus and Folkmans Transactional Model of Stress 1984, the specific aims of this study are to 1 examine the association of objective and subjective breast cancer risk with immune responses 2 examine the mediating role of psychological distress on the relationship between subjective breast cancer risk and immune responses 3 determine the moderating role of dispositional optimism on the relationship between subjective breast cancer risk and psychological distress and 4 assess the association between objective and subjective breast cancer risk in 126 healthy women with FH or without FH- family history of breast cancer in first-degree relatives FDRs.
- Genetic Engineering and Molecular Biology
- Medicine and Medical Research
- Stress Physiology