Breast Cancer Diagnosis Using Ultrasound and Diffusive Light
Final rept. 15 Aug 2000-14 Jul 2004
CONNECTICUT UNIV STORRS
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We have developed a novel near-infrared optical technique with ultrasound localization. We have made significant progress on using our technique to improve breast cancer diagnosis. Initial results with a group of more than 90 biopsied patients have shown that early stage invasive cancers present two-fold greater total hemoglobin concentration than fibroadenomas and benign lesions. Initial results of advanced cancers have shown that the angiogenesis distributions of larger cancers are highly distorted and heterogeneous and the distributions correlate with histological microvessel density counts. We believe that our unique technique has a great potential to improve current practice on breast cancer diagnosis and to monitor tumor vascular changes of advanced cancers during the chemotherapy treatment.
- Medicine and Medical Research