Accession Number:

ADA427170

Title:

Anti-Angiogenic Gene Therapy for Prostate Cancer

Descriptive Note:

Annual rept.

Corporate Author:

ALABAMA UNIV IN BIRMINGHAM

Personal Author(s):

Report Date:

2004-04-01

Pagination or Media Count:

61.0

Abstract:

One of the major implications of prostate cancer progression is bone metastasis. Primary therapies for neoplastic prostate disease have been prostectomy followed by chemotherapy and radiation therapy. Although these forms of palliative therapies have been successful in early detected prostate cancers, a problem in majority of the treated cases is the growth of radiationchemotherapy resistant tumor cells, which become refractory to treatment and exhibit an aggressive growth and metastatic profile. Thus, novel therapies that will control the process of recurrence and metastasis will have a profound clinical implication in the management of prostate cancer patients who undergo primary therapies.

Subject Categories:

  • Genetic Engineering and Molecular Biology
  • Anatomy and Physiology
  • Medicine and Medical Research

Distribution Statement:

APPROVED FOR PUBLIC RELEASE