Accession Number:

ADA426446

Title:

Extending the Refrigerated Storage of Red Blood Cells

Descriptive Note:

Final rept. 1 Nov 1999-31 May 2001

Corporate Author:

BOSTON UNIV MA BIOMEDICAL ENGINEERING

Personal Author(s):

Report Date:

2004-09-20

Pagination or Media Count:

7.0

Abstract:

Oxygen removal increases shelf-life and quality of refrigerated blood. The shelf life of our blood has been prolonged to a minimum of 12 weeks with survival equal to or greater than that of conventional 6 week storage. Increased quality is evident in increased ATP and DPG. This may result from increased binding of ATP and DPG to hemoglobin as a consequence of oxygen removal. The extent of quality improvement and prolonged shelf life are not yet maximal. Strong possibilities exist for further enhancing quality and prolonging shelf life. A self-regulating blood bag compatible with conventional storage facilities has been designed and awaits testing.

Subject Categories:

  • Medical Facilities, Equipment and Supplies

Distribution Statement:

APPROVED FOR PUBLIC RELEASE