Accession Number:

ADA426206

Title:

Targeting of Breast Tumors and Tumor Cells Using Inductive Magnetic Heating of Metallic Nanoparticles

Descriptive Note:

Annual rept. 19 May 2003-18 May 2004

Corporate Author:

MASSACHUSETTS UNIV AMHERST

Personal Author(s):

Report Date:

2004-06-01

Pagination or Media Count:

7.0

Abstract:

Our research in the first year has focused on the creation of nanoparticles designed for hyperthermic tumor ablation via magnetic field heating, and the development of equipment for genetic magnetic field generation. In the area of nanoparticle fabrication, we have changed our focus from metallic nanoparticles to superparamagnetic analogs. This change was made to avoid th high frequencies and energy fluxes required for metallic system . In our synthetic studies, we have developed particles that are stable and water soluble. In terms of equipment, we have discovered that the magnetic field generator described in the proposal was not powerful enough to obtain rapid heating of particles solutions. We are currently working with MSI industries to develop coils to be used with their 5 kW induction heating instrument.

Subject Categories:

  • Anatomy and Physiology
  • Medicine and Medical Research

Distribution Statement:

APPROVED FOR PUBLIC RELEASE