Accession Number:

ADA426106

Title:

Sulfur Mustard Damage to Cornea: Preventive Studies

Descriptive Note:

Annual rept. 1 May 2003-30 Apr 2004

Corporate Author:

MARYLAND UNIV BALTIMORE

Personal Author(s):

Report Date:

2004-05-01

Pagination or Media Count:

9.0

Abstract:

Studies are in progress to determine the efficacy and mechanism of a formulation containing anti-alkylating, antioxidants and metabolic accelerators present in VM against mustard induced skin toxicity. A preventive effect has been observed at the level of tissue morphology. Studies are in progress at the level of cellular metabolism, Here, CEES has been used as a representative compound simulating the action of sulfur mustard HD. It has been demonstrated for the first time that application of this formulation is effective even post exposure to mustard, Prophylaxis is not absolute. VM has been found to be useful even for inducing tissue regeneration adversely affected by the mustard compound

Subject Categories:

  • Anatomy and Physiology
  • Medicine and Medical Research
  • Chemical, Biological and Radiological Warfare

Distribution Statement:

APPROVED FOR PUBLIC RELEASE