Accession Number:

ADA416011

Title:

A Novel High-Resolution Positron Emission Tomography System for Measurement of Bone Metabolism

Descriptive Note:

Annual rept. 1 Sep 2001-31 Aug 2003

Corporate Author:

MASSACHUSETTS GENERAL HOSPITAL BOSTON

Personal Author(s):

Report Date:

2002-09-01

Pagination or Media Count:

17.0

Abstract:

The purpose of the work reported here is to develop high-resolution PET instrumentation for imaging the long bones. To-date a single plane prototype and a single plane second-generation instrumentation have been completed. The latter is currently being evaluated. A generalized multi-planar detector element has also been designed and evaluated experimentally and a volumetric instrument has been designed through simulation studies. A radiopharmaceutical for bone growth rate imaging, labeled C-tetracycline 11 has been developed for use in a demonstration study of imaging in a monkey osteoporosis model.

Subject Categories:

  • Medicine and Medical Research

Distribution Statement:

APPROVED FOR PUBLIC RELEASE